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Physiological Loading Can Restore the Proteoglycan Content in a Model of Early IVD Degeneration

A hallmark of early IVD degeneration is a decrease in proteoglycan content. Progression will eventually lead to matrix degradation, a decrease in weight bearing capacity and loss of disc height. In the final stages of IVD degradation, fissures appear in the annular ring allowing extrusion of the NP....

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Detalles Bibliográficos
Autores principales: Gawri, Rahul, Moir, Janet, Ouellet, Jean, Beckman, Lorne, Steffen, Thomas, Roughley, Peter, Haglund, Lisbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081577/
https://www.ncbi.nlm.nih.gov/pubmed/24992586
http://dx.doi.org/10.1371/journal.pone.0101233