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Physiological Loading Can Restore the Proteoglycan Content in a Model of Early IVD Degeneration
A hallmark of early IVD degeneration is a decrease in proteoglycan content. Progression will eventually lead to matrix degradation, a decrease in weight bearing capacity and loss of disc height. In the final stages of IVD degradation, fissures appear in the annular ring allowing extrusion of the NP....
Autores principales: | Gawri, Rahul, Moir, Janet, Ouellet, Jean, Beckman, Lorne, Steffen, Thomas, Roughley, Peter, Haglund, Lisbet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081577/ https://www.ncbi.nlm.nih.gov/pubmed/24992586 http://dx.doi.org/10.1371/journal.pone.0101233 |
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