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Targeting Histone Deacetylases for Cancer Therapy: From Molecular Mechanisms to Clinical Implications
Genetic abnormalities have been conventionally considered as hallmarks of cancer. However, studies over the past decades have demonstrated that epigenetic regulation also participates in the development of cancer. The fundamental patterns of epigenetic components, such as DNA methylation and histone...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081609/ https://www.ncbi.nlm.nih.gov/pubmed/25013383 http://dx.doi.org/10.7150/ijbs.9067 |