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Targeting Histone Deacetylases for Cancer Therapy: From Molecular Mechanisms to Clinical Implications

Genetic abnormalities have been conventionally considered as hallmarks of cancer. However, studies over the past decades have demonstrated that epigenetic regulation also participates in the development of cancer. The fundamental patterns of epigenetic components, such as DNA methylation and histone...

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Detalles Bibliográficos
Autores principales: Li, Zhiming, Zhu, Wei-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081609/
https://www.ncbi.nlm.nih.gov/pubmed/25013383
http://dx.doi.org/10.7150/ijbs.9067