Multi-Walled Carbon Nanotubes Impair Kv4.2/4.3 Channel Activities, Delay Membrane Repolarization and Induce Bradyarrhythmias in the Rat

PURPOSE: The potential hazardous effects of multi-walled carbon nanotubes (MWCNTs) on cardiac electrophysiology are seldom evaluated. This study aimed to investigate the impacts of MWCNTs on the Kv4/I (to) channel, action potential and heart rhythm and the underlying mechanisms. METHODS: HEK293 cell...

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Detalles Bibliográficos
Autores principales: Tan, Xiao-Qiu, Cheng, Xiu-Li, Zhang, Li, Wu, Bo-Wei, Liu, Qing-Hua, Meng, Jie, Xu, Hai-Yan, Cao, Ji-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081717/
https://www.ncbi.nlm.nih.gov/pubmed/24992664
http://dx.doi.org/10.1371/journal.pone.0101545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081717/
https://www.ncbi.nlm.nih.gov/pubmed/24992664
http://dx.doi.org/10.1371/journal.pone.0101545

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