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Innate Immune Responses and Rapid Control of Inflammation in African Green Monkeys Treated or Not with Interferon-Alpha during Primary SIVagm Infection

Chronic immune activation (IA) is considered as the driving force of CD4(+) T cell depletion and AIDS. Fundamental clues in the mechanisms that regulate IA could lie in natural hosts of SIV, such as African green monkeys (AGMs). Here we investigated the role of innate immune cells and IFN-α in the c...

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Detalles Bibliográficos
Autores principales: Jacquelin, Béatrice, Petitjean, Gaël, Kunkel, Désirée, Liovat, Anne-Sophie, Jochems, Simon P., Rogers, Kenneth A., Ploquin, Mickaël J., Madec, Yoann, Barré-Sinoussi, Françoise, Dereuddre-Bosquet, Nathalie, Lebon, Pierre, Le Grand, Roger, Villinger, François, Müller-Trutwin, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081777/
https://www.ncbi.nlm.nih.gov/pubmed/24991927
http://dx.doi.org/10.1371/journal.ppat.1004241