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Leptin- and Leptin Receptor-Deficient Rodent Models: Relevance for Human Type 2 Diabetes

Among the most widely used animal models in obesity-induced type 2 diabetes mellitus (T2DM) research are the congenital leptin- and leptin receptor-deficient rodent models. These include the leptin-deficient ob/ob mice and the leptin receptor-deficient db/db mice, Zucker fatty rats, Zucker diabetic...

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Detalles Bibliográficos
Autores principales: Wang, Bingxuan, P., Charukeshi Chandrasekera, Pippin, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082168/
https://www.ncbi.nlm.nih.gov/pubmed/24809394
http://dx.doi.org/10.2174/1573399810666140508121012