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Eccentric muscle challenge shows osteopontin polymorphism modulation of muscle damage

A promoter polymorphism of the osteopontin (OPN) gene (rs28357094) has been associated with multiple inflammatory states, severity of Duchenne muscular dystrophy (DMD) and muscle size in healthy young adults. We sought to define the mechanism of action of the polymorphism, using allele-specific in v...

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Detalles Bibliográficos
Autores principales: Barfield, Whitney L., Uaesoontrachoon, Kitipong, Wu, Chung-Sheih, Lin, Stephen, Chen, Yue, Wang, Paul C., Kanaan, Yasmine, Bond, Vernon, Hoffman, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082368/
https://www.ncbi.nlm.nih.gov/pubmed/24626632
http://dx.doi.org/10.1093/hmg/ddu118