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Dual Modifications Strategy to Quantify Neutral and Sialylated N-Glycans Simultaneously by MALDI-MS

[Image: see text] Differences in ionization efficiency among neutral and sialylated glycans prevent direct quantitative comparison by their respective mass spectrometric signals. To overcome this challenge, we developed an integrated chemical strategy, Dual Reactions for Analytical Glycomics (DRAG),...

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Detalles Bibliográficos
Autores principales: Zhou, Hui, Warren, Peter G., Froehlich, John W., Lee, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082391/
https://www.ncbi.nlm.nih.gov/pubmed/24766348
http://dx.doi.org/10.1021/ac500298a