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Improving analysis of transcription factor binding sites within ChIP-Seq data based on topological motif enrichment
BACKGROUND: Chromatin immunoprecipitation (ChIP) coupled to high-throughput sequencing (ChIP-Seq) techniques can reveal DNA regions bound by transcription factors (TF). Analysis of the ChIP-Seq regions is now a central component in gene regulation studies. The need remains strong for methods to impr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082612/ https://www.ncbi.nlm.nih.gov/pubmed/24927817 http://dx.doi.org/10.1186/1471-2164-15-472 |