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Improving analysis of transcription factor binding sites within ChIP-Seq data based on topological motif enrichment

BACKGROUND: Chromatin immunoprecipitation (ChIP) coupled to high-throughput sequencing (ChIP-Seq) techniques can reveal DNA regions bound by transcription factors (TF). Analysis of the ChIP-Seq regions is now a central component in gene regulation studies. The need remains strong for methods to impr...

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Detalles Bibliográficos
Autores principales:	Worsley Hunt, Rebecca, Mathelier, Anthony, del Peso, Luis, Wasserman, Wyeth W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082612/ https://www.ncbi.nlm.nih.gov/pubmed/24927817 http://dx.doi.org/10.1186/1471-2164-15-472

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