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Imaging intraorganellar Ca(2+) at subcellular resolution using CEPIA

The endoplasmic reticulum (ER) and mitochondria accumulate Ca(2+) within their lumens to regulate numerous cell functions. However, determining the dynamics of intraorganellar Ca(2+) has proven to be difficult. Here we describe a family of genetically encoded Ca(2+) indicators, named calcium-measuri...

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Detalles Bibliográficos
Autores principales: Suzuki, Junji, Kanemaru, Kazunori, Ishii, Kuniaki, Ohkura, Masamichi, Okubo, Yohei, Iino, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082642/
https://www.ncbi.nlm.nih.gov/pubmed/24923787
http://dx.doi.org/10.1038/ncomms5153