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Impact of ageing on the response and repertoire of influenza virus-specific CD4 T cells

BACKGROUND: Ageing has been shown to reduce CD8 T cell repertoire diversity and immune responses against influenza virus infection in mice. In contrast, less is known about the impact of ageing on CD4 T cell repertoire diversity and immune response to influenza virus infection. RESULTS: The CD4 T ce...

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Detalles Bibliográficos
Autores principales: Lanzer, Kathleen G, Johnson, Lawrence L, Woodland, David L, Blackman, Marcia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082670/
https://www.ncbi.nlm.nih.gov/pubmed/24999367
http://dx.doi.org/10.1186/1742-4933-11-9