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G(673) could be a novel mutational hot spot for intragenic suppressors of pheS5 lesion in Escherichia coli

The pheS5 Ts mutant of Escherichia coli defined by a G(293) → A(293) transition, which is responsible for thermosensitive Phenylalanyl-tRNA synthetase has been well studied at both biochemical and molecular level but genetic analyses pertaining to suppressors of pheS5 were hard to come by. Here we h...

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Detalles Bibliográficos
Autores principales: Ponmani, Thangaraj, Munavar, M Hussain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082710/
https://www.ncbi.nlm.nih.gov/pubmed/24811065
http://dx.doi.org/10.1002/mbo3.161