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Identification of novel non‐coding RNA‐based negative feedback regulating the expression of the oncogenic transcription factor GLI1

Non‐coding RNAs are a complex class of nucleic acids, with growing evidence supporting regulatory roles in gene expression. Here we identify a non‐coding RNA located head‐to‐head with the gene encoding the Glioma‐associated oncogene 1 (GLI1), a transcriptional effector of multiple cancer‐associated...

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Detalles Bibliográficos
Autores principales: Villegas, Victoria E., Rahman, Mohammed Ferdous-Ur, Fernandez-Barrena, Maite G., Diao, Yumei, Liapi, Eleni, Sonkoly, Enikö, Ståhle, Mona, Pivarcsi, Andor, Annaratone, Laura, Sapino, Anna, Ramírez Clavijo, Sandra, Bürglin, Thomas R., Shimokawa, Takashi, Ramachandran, Saraswathi, Kapranov, Philipp, Fernandez-Zapico, Martin E., Zaphiropoulos, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082767/
https://www.ncbi.nlm.nih.gov/pubmed/24726458
http://dx.doi.org/10.1016/j.molonc.2014.03.009