Cargando…

Stable expression of H1C2 monoclonal antibody in NS0 and CHO cells using pFUSE and UCOE expression system

From our recent publications, it was found that the deimmunization method (Dharshanan et al. (2012) Sci Res Essays 7:2288–2299) should be applied for the development of humanized anti-C2 monoclonal antibody (H1C2 mAb). However, the overlapping-PCR mutagenesis procedure used to insert the variable re...

Descripción completa

Detalles Bibliográficos
Autores principales: Dharshanan, Suba, Chong, Heilly, Cheah, Swee Hung, Zamrod, Zulkeflie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082778/
https://www.ncbi.nlm.nih.gov/pubmed/23881539
http://dx.doi.org/10.1007/s10616-013-9615-x