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Stable expression of H1C2 monoclonal antibody in NS0 and CHO cells using pFUSE and UCOE expression system
From our recent publications, it was found that the deimmunization method (Dharshanan et al. (2012) Sci Res Essays 7:2288–2299) should be applied for the development of humanized anti-C2 monoclonal antibody (H1C2 mAb). However, the overlapping-PCR mutagenesis procedure used to insert the variable re...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082778/ https://www.ncbi.nlm.nih.gov/pubmed/23881539 http://dx.doi.org/10.1007/s10616-013-9615-x |