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Insulin Blocks Glutamate-Induced Neurotoxicity in Differentiated SH-SY5Y Neuronal Cells

Insulin is a cytokine which promotes cell growth. Recently, a few published reports on insulin in different cell lines support the antiapoptotic effect of insulin. But the reports fail to explain the role of insulin in modulating glutamate-mediated neuronal cell death through excitotoxicity. Thus, w...

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Detalles Bibliográficos
Autores principales: Nampoothiri, Madhavan, Reddy, Neetinkumar D., John, Jessy, Kumar, Nitesh, Kutty Nampurath, Gopalan, Rao Chamallamudi, Mallikarjuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082871/
https://www.ncbi.nlm.nih.gov/pubmed/25018588
http://dx.doi.org/10.1155/2014/674164