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Evolutionally dynamic L1 regulation in embryonic stem cells

Mobile elements are important evolutionary forces that challenge genomic integrity. Long interspersed element-1 (L1, also known as LINE-1) is the only autonomous transposon still active in the human genome. It displays an unusual pattern of evolution, with, at any given time, a single active L1 line...

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Detalles Bibliográficos
Autores principales: Castro-Diaz, Nathaly, Ecco, Gabriela, Coluccio, Andrea, Kapopoulou, Adamandia, Yazdanpanah, Benyamin, Friedli, Marc, Duc, Julien, Jang, Suk Min, Turelli, Priscilla, Trono, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083085/
https://www.ncbi.nlm.nih.gov/pubmed/24939876
http://dx.doi.org/10.1101/gad.241661.114