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CNB-001 a Novel Curcumin Derivative, Guards Dopamine Neurons in MPTP Model of Parkinson's Disease

Copious experimental and postmortem studies have shown that oxidative stress mediated degeneration of nigrostriatal dopaminergic neurons underlies Parkinson's disease (PD) pathology. CNB-001, a novel pyrazole derivative of curcumin, has recently been reported to possess various neuroprotective...

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Detalles Bibliográficos
Autores principales: Jayaraj, Richard L., Elangovan, Namasivayam, Manigandan, Krishnan, Singh, Sonu, Shukla, Shubha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083212/
https://www.ncbi.nlm.nih.gov/pubmed/25025041
http://dx.doi.org/10.1155/2014/236182