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WASH complex regulates Arp2/3 complex for actin-based polar body extrusion in mouse oocytes

Prior to their fertilization, oocytes undergo asymmetric division, which is regulated by actin filaments. Recently, WASH complex were identified as actin nucleation promoting factors (NPF) that activated Arp2/3 complex. However, the roles of WASH complex remain uncertain, particularly for oocyte pol...

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Detalles Bibliográficos
Autores principales: Wang, Fei, Zhang, Liang, Zhang, Guang-Li, Wang, Zhen-Bo, Cui, Xiang-Shun, Kim, Nam-Hyung, Sun, Shao-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083260/
https://www.ncbi.nlm.nih.gov/pubmed/24998208
http://dx.doi.org/10.1038/srep05596