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Developmental programming by high fructose decreases phosphorylation efficiency in aging offspring brain mitochondria, correlating with enhanced UCP5 expression

Fructose has recently been observed to affect brain metabolism and cognitive function in adults. Yet, possible late-onset effects by gestational fructose exposure have not been examined. We evaluated mitochondrial function in the brain of aging (15 months) male offspring of Fischer F344 rat dams fed...

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Detalles Bibliográficos
Autores principales: Mortensen, Ole H, Larsen, Lea H, Ørstrup, Laura KH, Hansen, Lillian HL, Grunnet, Niels, Quistorff, Bjørn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083386/
https://www.ncbi.nlm.nih.gov/pubmed/24756078
http://dx.doi.org/10.1038/jcbfm.2014.72