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Developmental programming by high fructose decreases phosphorylation efficiency in aging offspring brain mitochondria, correlating with enhanced UCP5 expression
Fructose has recently been observed to affect brain metabolism and cognitive function in adults. Yet, possible late-onset effects by gestational fructose exposure have not been examined. We evaluated mitochondrial function in the brain of aging (15 months) male offspring of Fischer F344 rat dams fed...
Autores principales: | Mortensen, Ole H, Larsen, Lea H, Ørstrup, Laura KH, Hansen, Lillian HL, Grunnet, Niels, Quistorff, Bjørn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083386/ https://www.ncbi.nlm.nih.gov/pubmed/24756078 http://dx.doi.org/10.1038/jcbfm.2014.72 |
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