High burden of private mutations due to explosive human population growth and purifying selection

BACKGROUND: Recent studies have shown that human populations have experienced a complex demographic history, including a recent epoch of rapid population growth that led to an excess in the proportion of rare genetic variants in humans today. This excess can impact the burden of private mutations fo...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Keinan, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083409/
https://www.ncbi.nlm.nih.gov/pubmed/25056720
http://dx.doi.org/10.1186/1471-2164-15-S4-S3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083409/
https://www.ncbi.nlm.nih.gov/pubmed/25056720
http://dx.doi.org/10.1186/1471-2164-15-S4-S3

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