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High burden of private mutations due to explosive human population growth and purifying selection
BACKGROUND: Recent studies have shown that human populations have experienced a complex demographic history, including a recent epoch of rapid population growth that led to an excess in the proportion of rare genetic variants in humans today. This excess can impact the burden of private mutations fo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083409/ https://www.ncbi.nlm.nih.gov/pubmed/25056720 http://dx.doi.org/10.1186/1471-2164-15-S4-S3 |