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Feature-based multiple models improve classification of mutation-induced stability changes
BACKGROUND: Reliable prediction of stability changes in protein variants is an important aspect of computational protein design. A number of machine learning methods that allow a classification of stability changes knowing only the sequence of the protein emerged. However, their performance on amino...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083411/ https://www.ncbi.nlm.nih.gov/pubmed/25057118 http://dx.doi.org/10.1186/1471-2164-15-S4-S6 |