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Endoplasmic Reticulum Calcium, Stress and Cell-to-Cell Adhesion

Darier's Disease (DD) is caused by mutations in the endoplasmic reticulum (ER) Ca(2+) ATPase ATP2A2 (protein SERCA2). Current treatment modalities are ineffective for many patients. This report shows that impaired SERCA2 function, both in DD keratinocytes and in normal keratinocytes treated wit...

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Detalles Bibliográficos
Autor principal: Mauro, Theodora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083462/
https://www.ncbi.nlm.nih.gov/pubmed/24924761
http://dx.doi.org/10.1038/jid.2014.97