FOXO1 Inhibition Yields Functional Insulin-Producing Cells In Human Gut Organoid Cultures

Generation of surrogate sources of insulin-producing β-cells remains a goal of diabetes therapy. While most efforts have been directed at differentiating embryonic or induced pluripotent stem (iPS) cells into β-like-cells through endodermal progenitors, we have shown that gut endocrine progenitor ce...

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Detalles Bibliográficos
Autores principales: Bouchi, Ryotaro, Foo, Kylie S., Hua, Haiqing, Tsuchiya, Kyoichiro, Ohmura, Yoshiaki, Sandoval, P. Rodrigo, Ratner, Lloyd E., Egl, Dieter, Leibel, Rudolph L., Accili, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083475/
https://www.ncbi.nlm.nih.gov/pubmed/24979718
http://dx.doi.org/10.1038/ncomms5242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083475/
https://www.ncbi.nlm.nih.gov/pubmed/24979718
http://dx.doi.org/10.1038/ncomms5242

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