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FOXO1 Inhibition Yields Functional Insulin-Producing Cells In Human Gut Organoid Cultures
Generation of surrogate sources of insulin-producing β-cells remains a goal of diabetes therapy. While most efforts have been directed at differentiating embryonic or induced pluripotent stem (iPS) cells into β-like-cells through endodermal progenitors, we have shown that gut endocrine progenitor ce...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083475/ https://www.ncbi.nlm.nih.gov/pubmed/24979718 http://dx.doi.org/10.1038/ncomms5242 |