Fast disintegrating crystalline solid dispersions of simvastatin for incorporation into orodispersible tablets

AIM: Spray dried solid dispersion (SDP) of crystalline simvastatin (SIM) in a fast disintegrating matrix of superdisintegrants was studied as a method to enhance SIM dispersibility, rheology, compactibility and compressibility for incorporation into orodispersible tablets (ODTs). MATERIALS AND METHO...

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Detalles Bibliográficos
Autores principales: Pabari, Ritesh M, Jamil, Asha, Kelly, John G, Ramtoola, Zebunnissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083534/
https://www.ncbi.nlm.nih.gov/pubmed/25006549
http://dx.doi.org/10.4103/2230-973X.133029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083534/
https://www.ncbi.nlm.nih.gov/pubmed/25006549
http://dx.doi.org/10.4103/2230-973X.133029

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