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Fast disintegrating crystalline solid dispersions of simvastatin for incorporation into orodispersible tablets

AIM: Spray dried solid dispersion (SDP) of crystalline simvastatin (SIM) in a fast disintegrating matrix of superdisintegrants was studied as a method to enhance SIM dispersibility, rheology, compactibility and compressibility for incorporation into orodispersible tablets (ODTs). MATERIALS AND METHO...

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Detalles Bibliográficos
Autores principales:	Pabari, Ritesh M, Jamil, Asha, Kelly, John G, Ramtoola, Zebunnissa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2014
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083534/ https://www.ncbi.nlm.nih.gov/pubmed/25006549 http://dx.doi.org/10.4103/2230-973X.133029

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