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The Par3-Like Polarity Protein, Par3L, is Essential for Mammary Stem Cell Maintenance

The Par polarity proteins play key roles in asymmetric division of Drosophila stem cells; however, whether the same mechanisms control stem cells in mammals is controversial. Although necessary for mammary gland morphogenesis, Par3 is not essential for mammary stem cell function. We discovered that,...

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Detalles Bibliográficos
Autores principales: Huo, Yongliang, Macara, Ian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083567/
https://www.ncbi.nlm.nih.gov/pubmed/24859006
http://dx.doi.org/10.1038/ncb2969