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Sequence Variation in the E2-Binding Domain of HPV16 and Biological Function Evaluation in Tunisian Cervical Cancers

HPV16 E2 variants have different effects on the transcriptional activity of the LCR. In this study, we examined the nucleotide and amino acid sequence variation within the HPV16 E2 gene and to correlate with disease progression. E2 gene disruption was detected by PCR amplification of the entire E2 g...

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Detalles Bibliográficos
Autores principales: Kahla, Saloua, Kochbati, Lotfi, Hammami, Samia, Chanoufi, Mohamed Badis, Maalej, Mongi, Oueslati, Ridha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083599/
https://www.ncbi.nlm.nih.gov/pubmed/25032221
http://dx.doi.org/10.1155/2014/639321