A Trio-Rac1-PAK1 signaling axis drives invadopodia disassembly

Rho family GTPases control cell migration and participate in the regulation of cancer metastasis. Invadopodia, associated with invasive tumor cells, are crucial for cellular invasion and metastasis. To study Rac1 GTPase in invadopodia dynamics, we developed a genetically-encoded, single-chain Rac1 F...

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Detalles Bibliográficos
Autores principales: Moshfegh, Yasmin, Bravo-Cordero, Jose Javier, Miskolci, Veronika, Condeelis, John, Hodgson, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083618/
https://www.ncbi.nlm.nih.gov/pubmed/24859002
http://dx.doi.org/10.1038/ncb2972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083618/
https://www.ncbi.nlm.nih.gov/pubmed/24859002
http://dx.doi.org/10.1038/ncb2972

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