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Downregulation of Transketolase Activity Is Related to Inhibition of Hippocampal Progenitor Cell Proliferation Induced by Thiamine Deficiency

In animal experiments, hippocampal neurogenesis and the activity of thiamine-dependent transketolase decrease markedly under conditions of thiamine deficiency. To further investigate the effect of thiamine deficiency on the proliferation of hippocampal progenitor cells (HPCs) and the potential mecha...

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Detalles Bibliográficos
Autores principales: Zhao, Yanling, Wu, Yiying, Hu, Haolu, Cai, Jinghui, Ning, Min, Ni, Xiushi, Zhong, Chunjiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083768/
https://www.ncbi.nlm.nih.gov/pubmed/25028661
http://dx.doi.org/10.1155/2014/572915