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Chronic Neuroinflammation in Alzheimer's Disease: New Perspectives on Animal Models and Promising Candidate Drugs

Chronic neuroinflammation is now considered one of the major factors in the pathogenesis of Alzheimer's disease (AD). However, the most widely used transgenic AD models (overexpressing mutated forms of amyloid precursor protein, presenilin, and/or tau) do not demonstrate the degree of inflammat...

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Detalles Bibliográficos
Autores principales: Millington, Christopher, Sonego, Sandra, Karunaweera, Niloo, Rangel, Alejandra, Aldrich-Wright, Janice R., Campbell, Iain L., Gyengesi, Erika, Münch, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083880/
https://www.ncbi.nlm.nih.gov/pubmed/25025046
http://dx.doi.org/10.1155/2014/309129