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Chronic Neuroinflammation in Alzheimer's Disease: New Perspectives on Animal Models and Promising Candidate Drugs
Chronic neuroinflammation is now considered one of the major factors in the pathogenesis of Alzheimer's disease (AD). However, the most widely used transgenic AD models (overexpressing mutated forms of amyloid precursor protein, presenilin, and/or tau) do not demonstrate the degree of inflammat...
Autores principales: | Millington, Christopher, Sonego, Sandra, Karunaweera, Niloo, Rangel, Alejandra, Aldrich-Wright, Janice R., Campbell, Iain L., Gyengesi, Erika, Münch, Gerald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083880/ https://www.ncbi.nlm.nih.gov/pubmed/25025046 http://dx.doi.org/10.1155/2014/309129 |
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