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Hirano bodies differentially modulate cell death induced by tau and the amyloid precursor protein intracellular domain

BACKGROUND: Hirano bodies are actin-rich paracrystalline inclusions found in brains of patients with Alzheimer’s disease (AD), frontotemporal dementia (FTD), and in normal aged individuals. Although studies of post-mortem brain tissue provide clues of etiology, the physiological function of Hirano b...

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Detalles Bibliográficos
Autores principales: Spears, William, Furgerson, Matthew, Sweetnam, John Michael, Evans, Parker, Gearing, Marla, Fechheimer, Marcus, Furukawa, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084581/
https://www.ncbi.nlm.nih.gov/pubmed/24929931
http://dx.doi.org/10.1186/1471-2202-15-74