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Hirano bodies differentially modulate cell death induced by tau and the amyloid precursor protein intracellular domain
BACKGROUND: Hirano bodies are actin-rich paracrystalline inclusions found in brains of patients with Alzheimer’s disease (AD), frontotemporal dementia (FTD), and in normal aged individuals. Although studies of post-mortem brain tissue provide clues of etiology, the physiological function of Hirano b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084581/ https://www.ncbi.nlm.nih.gov/pubmed/24929931 http://dx.doi.org/10.1186/1471-2202-15-74 |