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Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

[Image: see text] We report the discovery of a series of new drug leads that have potent activity against Mycobacterium tuberculosis as well as against other bacteria, fungi, and a malaria parasite. The compounds are analogues of the new tuberculosis (TB) drug SQ109 (1), which has been reported to a...

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Detalles Bibliográficos
Autores principales: Li, Kai, Schurig-Briccio, Lici A., Feng, Xinxin, Upadhyay, Ashutosh, Pujari, Venugopal, Lechartier, Benoit, Fontes, Fabio L., Yang, Hongliang, Rao, Guodong, Zhu, Wei, Gulati, Anmol, No, Joo Hwan, Cintra, Giovana, Bogue, Shannon, Liu, Yi-Liang, Molohon, Katie, Orlean, Peter, Mitchell, Douglas A., Freitas-Junior, Lucio, Ren, Feifei, Sun, Hong, Jiang, Tong, Li, Yujie, Guo, Rey-Ting, Cole, Stewart T., Gennis, Robert B., Crick, Dean C., Oldfield, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084622/
https://www.ncbi.nlm.nih.gov/pubmed/24568559
http://dx.doi.org/10.1021/jm500131s