Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes

MicroRNAs (miRNAs), small RNA molecules that post-transcriptionally regulate mRNA expression, are crucial in diverse developmental and physiological programs and their misregulation can lead to disease. Chemically modified oligonucleotides have been developed to modulate miRNA activity for therapeut...

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Detalles Bibliográficos
Autores principales: Hogan, Daniel J., Vincent, Thomas M., Fish, Sarah, Marcusson, Eric G., Bhat, Balkrishen, Chau, B. Nelson, Zisoulis, Dimitrios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084633/
https://www.ncbi.nlm.nih.gov/pubmed/24992387
http://dx.doi.org/10.1371/journal.pone.0100951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084633/
https://www.ncbi.nlm.nih.gov/pubmed/24992387
http://dx.doi.org/10.1371/journal.pone.0100951

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