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Phosphorylation of Serine 106 in Asef2 Regulates Cell Migration and Adhesion Turnover
[Image: see text] Asef2, a 652-amino acid protein, is a guanine nucleotide exchange factor (GEF) that regulates cell migration and other processes via activation of Rho family GTPases, including Rac. Binding of the tumor suppressor adenomatous polyposis coli (APC) to Asef2 is known to induce its GEF...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084842/ https://www.ncbi.nlm.nih.gov/pubmed/24874604 http://dx.doi.org/10.1021/pr5001384 |