The C-Score: A Bayesian Framework to Sharply Improve Proteoform Scoring in High-Throughput Top Down Proteomics

[Image: see text] The automated processing of data generated by top down proteomics would benefit from improved scoring for protein identification and characterization of highly related protein forms (proteoforms). Here we propose the “C-score” (short for Characterization Score), a Bayesian approach...

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Detalles Bibliográficos
Autores principales: LeDuc, Richard D., Fellers, Ryan T., Early, Bryan P., Greer, Joseph B., Thomas, Paul M., Kelleher, Neil L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084843/
https://www.ncbi.nlm.nih.gov/pubmed/24922115
http://dx.doi.org/10.1021/pr401277r

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084843/
https://www.ncbi.nlm.nih.gov/pubmed/24922115
http://dx.doi.org/10.1021/pr401277r

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