Intramuscular adipogenesis is inhibited by myo-endothelial progenitors with functioning Bmpr1a signaling

Developing human muscle contains inter-myofiber progenitors expressing Bmp-receptor 1a (Bmpr1a) and Myf5 that respond to stimulation with Bmp4. Here we ablate Bmpr1a in Myf5- and MyoD-expressing cells in vivo. Mutant mice reveal increased intramuscular fat and reduced myofiber size in selected muscl...

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Detalles Bibliográficos
Autores principales: Huang, Ping, Schulz, Tim J., Beauvais, Ariane, Tseng, Yu-Hua, Gussoni, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084855/
https://www.ncbi.nlm.nih.gov/pubmed/24898859
http://dx.doi.org/10.1038/ncomms5063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084855/
https://www.ncbi.nlm.nih.gov/pubmed/24898859
http://dx.doi.org/10.1038/ncomms5063

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