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Intramuscular adipogenesis is inhibited by myo-endothelial progenitors with functioning Bmpr1a signaling
Developing human muscle contains inter-myofiber progenitors expressing Bmp-receptor 1a (Bmpr1a) and Myf5 that respond to stimulation with Bmp4. Here we ablate Bmpr1a in Myf5- and MyoD-expressing cells in vivo. Mutant mice reveal increased intramuscular fat and reduced myofiber size in selected muscl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084855/ https://www.ncbi.nlm.nih.gov/pubmed/24898859 http://dx.doi.org/10.1038/ncomms5063 |