Developmental Lead Exposure Alters Synaptogenesis through Inhibiting Canonical Wnt Pathway In Vivo and In Vitro

Lead (Pb) exposure has been implicated in the impairment of synaptic plasticity in the developing hippocampus, but the mechanism remains unclear. Here, we investigated whether developmental lead exposure affects the dendritic spine formation through Wnt signaling pathway in vivo and in vitro. Spragu...

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Detalles Bibliográficos
Autores principales: Hu, Fan, Xu, Li, Liu, Zhi-Hua, Ge, Meng-Meng, Ruan, Di-Yun, Wang, Hui-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084981/
https://www.ncbi.nlm.nih.gov/pubmed/24999626
http://dx.doi.org/10.1371/journal.pone.0101894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084981/
https://www.ncbi.nlm.nih.gov/pubmed/24999626
http://dx.doi.org/10.1371/journal.pone.0101894

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