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Gender Effect in Experimental Models of Human Medulloblastoma: Does the Estrogen Receptor β Signaling Play a Role?

BACKGROUND: The male-to-female sex ratio for medulloblastoma (MB) is approximately 1.5∶1, female gender being also a favorable prognostic factor. This study aimed at evaluating the impact of gender on MB tumorigenesis. METHODS: In vitro activity of 17β-estradiol (E(2)), DPN [2,3-bis(4-hydroxyphenyl)...

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Detalles Bibliográficos
Autores principales: Ciucci, Alessandra, Meco, Daniela, De Stefano, Ilaria, Travaglia, Daniele, Zannoni, Gian Franco, Scambia, Giovanni, Riccardi, Riccardo, Saran, Anna, Mancuso, Mariateresa, Gallo, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084991/
https://www.ncbi.nlm.nih.gov/pubmed/25000562
http://dx.doi.org/10.1371/journal.pone.0101623