Impact of P-Site tRNA and Antibiotics on Ribosome Mediated Protein Folding: Studies Using the Escherichia coli Ribosome

BACKGROUND: The ribosome, which acts as a platform for mRNA encoded polypeptide synthesis, is also capable of assisting in folding of polypeptide chains. The peptidyl transferase center (PTC) that catalyzes peptide bond formation resides in the domain V of the 23S rRNA of the bacterial ribosome. Pro...

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Detalles Bibliográficos
Autores principales: Mondal, Surojit, Pathak, Bani Kumar, Ray, Sutapa, Barat, Chandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085065/
https://www.ncbi.nlm.nih.gov/pubmed/25000563
http://dx.doi.org/10.1371/journal.pone.0101293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085065/
https://www.ncbi.nlm.nih.gov/pubmed/25000563
http://dx.doi.org/10.1371/journal.pone.0101293

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