Comparative analysis of human and mouse immunoglobulin variable heavy regions from IMGT/LIGM-DB with IMGT/HighV-QUEST

BACKGROUND: Immunoglobulin (IG) complementarity determining region (CDR) includes VH CDR1, VH CDR2, VH CDR3, VL CDR1, VL CDR2 and VL CDR3. Of these, VH CDR3 plays a dominant role in recognizing and binding antigens. Three major mechanisms are involved in the formation of the VH repertoire: germline...

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Detalles Bibliográficos
Autores principales: Shi, Bin, Ma, Long, He, Xiaoyan, Wang, Xiaomei, Wang, Peng, Zhou, Li, Yao, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085081/
https://www.ncbi.nlm.nih.gov/pubmed/24992938
http://dx.doi.org/10.1186/1742-4682-11-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085081/
https://www.ncbi.nlm.nih.gov/pubmed/24992938
http://dx.doi.org/10.1186/1742-4682-11-30

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