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Spot quantification in two dimensional gel electrophoresis image analysis: comparison of different approaches and presentation of a novel compound fitting algorithm
BACKGROUND: Various computer-based methods exist for the detection and quantification of protein spots in two dimensional gel electrophoresis images. Area-based methods are commonly used for spot quantification: an area is assigned to each spot and the sum of the pixel intensities in that area, the...
Autores principales: | Brauner, Jan M, Groemer, Teja W, Stroebel, Armin, Grosse-Holz, Simon, Oberstein, Timo, Wiltfang, Jens, Kornhuber, Johannes, Maler, Juan Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085234/ https://www.ncbi.nlm.nih.gov/pubmed/24915860 http://dx.doi.org/10.1186/1471-2105-15-181 |
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