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Functional analysis of the acetylation of human p53 in DNA damage responses

As a critical tumor suppressor, p53 is inactivated in human cancer cells by somatic gene mutation or disruption of pathways required for its activation. Therefore, it is critical to elucidate the mechanism underlying p53 activation after genotoxic and cellular stresses. Accumulating evidence has ind...

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Detalles Bibliográficos
Autores principales: Chung, Sun-Ku, Zhu, Shengyun, Xu, Yang, Fu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085286/
https://www.ncbi.nlm.nih.gov/pubmed/24691905
http://dx.doi.org/10.1007/s13238-014-0048-x